Rapid Developability Assessment Of Early Phase Molecules: Parallel Screening Of Enabling Technologies And Use Of PBPK Modeling

Scaling-up liquid formulations can present a number of challenges and headaches. This is especially true for complex solutions, suspensions and emulsions as well as biologics, sterile products, potent compounds and sensitive APIs. In this webcast, learn about potential formulation and filling issues when transitioning a liquid formulation from feasibility through commercialization.

Product development experts share insights on a variety of formulation issues including mixing, solubility, microfluidization, viscosity, filtration and special API handling, with discussed solutions based on Catalent’s expertise in complex formulation. Equipment for liquid-filling and scale-up will be discussed with a focus on potential applications of advanced aseptic Blow-Fill-Seal (BFS) technology.Achieving success in early development is essential in progressing to your molecule’s next milestone. While solving solubility is a major hurdle to overcome in early development, there are additional biopharmaceutical challenges to consider on the path to commercialization.

This webinar will demonstrate how additional screening strategies can help you better understand your molecule and predict its future success on the path to commercialization. Experts will  share a recent case study that illustrates how to use PBPK modeling, the developability classification system¹ and the biopharmaceutics drug distribution classification system² together to facilitate the development of a molecule.