04.17.24 -- The Next Evolution In Immuno-Oncology

Use of a high salt concentration during the cell lysis step in AAV production delivers higher titers and massively improves virus infectivity. However, high salt conditions inhibit activity of conventional endonucleases used for DNA digestion. Learn how our NEW GMP grade Benzonase® Salt Tolerant endonuclease enables incorporation of high salt concentrations during this midstream step.

Review the efficacy of fast stable pools in generating purified products at an early stage and learn how to accelerate the journey toward first-in-human trials and proof-of-concept studies.

Examine considerations for the series of characterizations necessary to ensure the efficacy of a packaging or device component and final drug delivery system.

Securing the right plasmid for an application can be a complex endeavor. Core to this is selecting a supplier with the quality assurance protocols and GMPs to facilitate optimized plasmid production.

Navigating the Clinical Trials Regulation (CTR) in the EU presents challenges amid evolving guidelines. Recent updates, like transparency rule changes, aim to streamline compliance.

Explore a stepwise approach for integrating process intensification principles into an existing process to increase productivity, reduce costs, and improve process sustainability.

Tracking billing and expenditures with notepads and Excel spreadsheets isn’t enough to meet client needs or auditing regulations. Find a new software solution CROs are using to be more proficient.

API-sparing development techniques and identification of the appropriate scalable formulation technology to improve solubility and enhance oral bioavailability can increase your chances of success.