Article | February 10, 2026

Genentech More Than Doubles Initial Holly Springs Investment To $2B

By Chris Capot, NCBiotech

Genentech’s decision to more than double its planned investment in Holly Springs marks a major expansion of North Carolina’s biomanufacturing landscape. The company is increasing its commitment from $700 million to $2 billion, boosting output at its new high‑volume fill‑finish facility and raising total job creation to more than 500 roles. The project reflects a broader strategy to strengthen domestic production and long‑term supply resilience, supported by Holly Springs’ highly skilled workforce, academic partnerships, and proximity to the Research Triangle’s established life science ecosystem. With average salaries far above the county benchmark and a projected community payroll impact exceeding $50 million annually, the expansion underscores both the regional economic significance and the state’s growing prominence as a biotech hub.

Explore how this development aligns with national manufacturing priorities and the future of U.S.-based biopharma production.

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North Carolina Biotechnology Center