Companies To Watch

The Companies to Watch column spotlights small, entrepreneurial biopharma companies that are developing their own products (not just a platform) with little or no press coverage to date, and offering an interesting story involving useful business lessons.

  • Companies To Watch: Abivax
    Companies To Watch: Abivax

    With 24 employees, Paris-based Abivax is in Phase 2 clinical development of its lead drug candidate, which is a potential functional cure for HIV infection.  It has also recently spawned an early clinical program in inflammatory bowel disease (IBD).

  • Companies To Watch: Madrigal Pharmaceuticals
    Companies To Watch: Madrigal Pharmaceuticals

    Madrigal Pharmaceuticals is taking on NASH and other liver diseases by targeting the thyroid hormone beta receptor. The company expects to begin seeing top line Phase 2 trial results in late 2017, with more released in 2018.

  • Companies To Watch: Arena Pharmaceuticals
    Companies To Watch: Arena Pharmaceuticals

    By early 2016, Arena’s board decided to remake the company, beginning with new management and a new strategy. Since then, the company has evolved back to a core drug development platform.

  • Companies To Watch: ProMIS Neurosciences
    Companies To Watch: ProMIS Neurosciences

    ProMIS Neurosciences believes inaccurate targeting of mAbs is to blame, in fact, for lack of progress against Alzheimer’s disease.

  • Companies To Watch: GeNeuro
    Companies To Watch: GeNeuro

    Outside skepticism about GeNeuro’s scientific concept has made fund-raising even harder than usual for a startup. But the Swiss company has found considerable support in Europe.

  • Companies To Watch: Frequency Therapeutics
    Companies To Watch: Frequency Therapeutics

    Frequency Therapeutics is an early-stage developer of small molecule drugs to activate “progenitor cells” and restore healthy tissue. Its lead program is in treating hearing loss by regenerating sensory cells in the inner ear, for which it is planning a Phase 1 trial to launch in mid-2018.

  • Companies To Watch: Noveome Biotherapeutics
    Companies To Watch: Noveome Biotherapeutics

    To heal the wounds — maintaining and restoring cellular homeostasis with novel secretomes.

  • Companies To Watch: Aridis Pharmaceuticals
    Companies To Watch: Aridis Pharmaceuticals

    An anti-infective immunotherapy developer on a mission to replace antibiotics with engineered antibodies and novel mechanisms.

  • Companies To Watch: Edge Therapeutics
    Companies To Watch: Edge Therapeutics

    In Phase 3 with an innovatively delivered drug to treat a deadly complication of ruptured brain aneurysm.

  • A Progress Report On The 2016 Companies To Watch
    A Progress Report On The 2016 Companies To Watch

    There is no grand plan for a whole year of Companies to Watch (CtW). Each month, a single candidate makes the cut for a single column. Nevertheless, patterns emerge among the CtWs as the year progresses and come into focus as it ends.

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