Companies To Watch

The Companies to Watch column spotlights small, entrepreneurial biopharma companies that are developing their own products (not just a platform) with little or no press coverage to date, and offering an interesting story involving useful business lessons.

  • Companies To Watch: Carisma Therapeutics

    Carisma Therapeutics is a private company developing CAR-M (chimeric antigen receptor macrophage) as an alternative to CAR-T (CAR-T cell) and potential treatment for solid tumors rather than just liquid cancers.

  • Companies To Watch: PhaseBio

    PhaseBio is a small, public company aiming to enter a large-market therapeutic area: cardiovascular.

  • Companies To Watch: Akero Therapeutics

    Companies To Watch: Akero Therapeutics - Test-proofing a new metabolism drug to beat the liver disease, NASH

  • Companies To Watch: Artax Biopharma

    Artax Biopharma is challenging the immunosuppressive paradigm with a novel drug for autoimmune diseases.

  • Companies To Watch: Ridgeback Biotherapeutics

    Ridgeback Biotherapeutics is pitting new and potent antivirals versus COVID, Ebola, and other coronaviruses.

  • Companies To Watch: Osivax

    Osivax is developing universal vaccines for influenza, coronaviruses, and other infectious diseases such as malaria and human papillomavirus (HPV). Preclinical studies also have started on a coronavirus vaccine, which would include Covid-19.

  • Companies To Watch: CalciMedica

    “In a sense, the Covid association was a golden opportunity for our drug,” says Rachel Leheny, CEO of CalciMedica, a pharma focused on anti-inflammatories for pancreatitis that has now shifted to treatments for Covid-19 pneumonia.

  • Companies To Watch: Cidara Therapeutics

    Cidara Therapeutics is training its novel treatment and preventative for flu and other viral infections on Covid-19.

  • Companies To Watch: Equillium

    Equillium is keeping a close eye on the COVID-19 challenge, but sticking to acute GVHD, uncontrolled asthma, and lupus nephritis as primary inflammation targets.

  • Companies To Watch: Spring Bank Pharmaceuticals

    Spring Bank Pharmaceuticals is continuing clinical programs during the COVID-19 challenge and advancing novel approaches to cancer, inflammation, and viruses.

  • Companies To Watch: argenx

    Argenx is developing new antibody therapeutics for immunological diseases in the neuromuscular, hematology, oncology, and other areas. The company has a full pipeline of candidates and indications.

  • Companies To Watch: Neurana

    This 10-person startup in San Diego is aiming for muscle-spasm relief without sedation in a purified drug.

  • Companies To Watch: Adaptive Phage Therapeutics

    Adaptive Phage Therapeutics has created a large catalog of bacteria-killing viruses combined with a diagnostic test to identify and target specific bacterial strains infecting individual patients.

  • Companies To Watch: Imago BioSciences

    In developing a new drug for MPN diseases, Imago is entering a space where two potential competitors, Jakafi and Inrebic, both JAK (janus associated kinase) inhibitors, are already on the market.

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