Newsletter | December 13, 2023

12.13.23 -- Beyond AAV: Next-Gen Viral Vectors

SPONSOR

Accelerate Drug Development From Transfection To GMP

Accelerating progress from cell line development to the production of GMP drug substance for Phase 1 and Phase 2 clinical trials is essential for success. At the same time, the need to align activities with funding milestones or adhere to a stepwise investment strategy imposes cost constraints. Our accelerated mAb development program shortens development timelines for IgG1 and IgG4 monoclonal antibodies to nine months. Learn more here.

FEATURED ARTICLES

Moving Beyond AAV: The Next Generation Of Vectors In CGT

We catch up with Dr. Konstantin Konstantinov, CTO at Ring Therapeutics, and Ryan Crisman, Ph.D., cofounder and CTO at Umoja Biopharma, to get their thoughts on the future of new anellovirus vectors and existing lentiviral vector technology for in vivo gene delivery, respectively.

Top 2024 Clinical Trial Site Challenges: Staffing & Technology

Is there anything new that has popped up in the last year or so that has really affected how sites operate? Industry experts talk about some of the new challenges facing clinical trial sites in 2024.

Defining A Competitive Next-Gen RNA Therapeutic In 2024

To understand where our RNA therapeutics are today and to start singling out where the opportunities exist to craft the next generation of RNA therapeutics, Anna Rose Welch sat down with four RNA executives.

INDUSTRY INSIGHTS

How Life Sciences Companies Are Addressing Scope 3 Emissions

Scope 3 emissions are becoming a particularly pressing concern for life sciences companies going through net zero discussions with partners and suppliers as they combat climate change.

How PATs Improve Bioreactor Performance And Inline Monitoring

Accurately monitoring process parameters and bioreactor performance while leveraging PAT tools can lead to strong improvements in productivity, quality, and process stability.

Key Takeaways Of Annex 1: What It Means For Your Cold Chain Management

What are the practical implications of the latest Annex 1 update, specifically for cold chain management? Sartorius asked a few in-house experts for their thoughts on the subject.

Four Challenges That Stall Advanced Therapy Development

Many challenges can stall an advanced therapy’s development, the vast majority of them tied to inadequate preclinical planning and partner vetting.

Design Of Experiments Approach To Enabling Studies For Process Validation

A recent project applied process improvement methodology to the process validation step that ultimately provided not only an optimized, robust process but also an economic advantage.

DIGITAL EDITION

December 2023 Digital Edition

Inside you will find more on:

  • Executive Outlook
  • Supply Chain Challenges
  • Tomorrow's Leadership Skills
  • Real-World Data

View the digital edition.

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