Product/Service

CD34+ HSC LNP Kits

Source: Cytiva
HSC-Kit-Box-and-Vials_100ul_0324

Research Use Only (RUO) lipid nanoparticle (LNP) reagents to deliver RNA into hematopoietic stem cells (HSCs) for cell and gene therapy applications.

The CD34+ HSC LNP kit is an LNP reagent mix optimized for the delivery of mRNA or Cas9 mRNA/sgRNA into CD34+ HSCs. This reagent enables researchers to establish a clinically relevant and scalable method at the discovery and preclinical scale for ex vivo gene delivery and editing.

CD34+ HSC LNP kit offers the following benefits:

  • Optimized LNP formulation: Deliver RNA with high transfection efficiency by using an optimized proprietary LNP formulation*
  • High knockout efficiency: Achieve dose-dependent high efficiency gene knockdown and protein expression.
  • High cell yield and differentiation potential: Maintain high cell viability, yield, and differentiation potential post-editing.
  • Scale from discovery to preclinical: Scale up your ex vivo cell therapy research from discovery to preclinical using the NanoAssemblr™ platform.
  • Validated workflow: Optimized and validated with the CD34+ HSC cell manufacturing workflow.

*LNP composition in this research-use-only kit include ionizable lipid excipients that can be licensed for future clinical evaluation.