Article | April 22, 2025

Collaborative Approach Is Key To Successful CGT Clinical Trials

By Chris Learn, Parexel

For many professionals in the drug development industry, cell and gene therapies (CGT) represent a beacon of hope for patients in dire need of innovative treatments. This rapidly evolving field is opening up thrilling possibilities for addressing a broad spectrum of diseases. Notably, CGT has shown promise in providing genuine cures for conditions such as hemophilia, sickle cell disease, and certain forms of blindness and deafness. Despite the optimism surrounding CGT, the path to bringing these therapies from the lab to the patient is fraught with challenges. The complexities inherent in CGT trials pose unique obstacles for the trial sites tasked with administering these investigational drugs to test subjects. These trials often demand extensive resources and meticulous workflows, which can strain the capabilities of healthcare teams. Consequently, many trial sites find themselves under-resourced, struggling to meet the rigorous demands of CGT trials.

Explore how this resource strain can impede the progress of these potentially transformative treatments, which delays their availability to the patients who need them most.

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North Carolina Biotechnology Center