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Bispecific antibodies (bsAbs) are revolutionizing medicine by targeting two disease mechanisms simultaneously. However, the intricate structure of bsAbs presents a significant roadblock in their development and manufacturing. Learn how an innovative platform offers excellent pairing and significantly enhances productivity and quality.
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Samsung Biologics’ Cell Line Development Group has implemented a novel high-throughput screening method for analyzing a molecule’s sialic acid profile by measuring its binding affinity with lectin. For this assay, lectins, sugar-binding proteins highly specific to their associated sugar moieties, are leveraged to improve specificity.
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The biopharmaceutical industry is trending toward building process characterization systems and processes early in a project’s life cycle, enabling success for later-stage development. In parallel, work must be done to prepare development and manufacturing for that later stage, whether to enable studies or to commercialize the product.
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