Foot And Mouth Disease (FMD) Virus Vaccine: Filtration Strategies For Optimal Development And Purification

By Youness Cherradi, Youssef Gaabouri, Anissa Boumlic, Nargisse El Hajjami, Dr. Leonid Dudnikov

Foot-and-mouth disease (FMD) is a highly contagious and sometimes fatal viral disease that affects cloven-hoofed animals. Massive vaccination with at least 80% coverage is one of the control strategies implemented to prevent virus introduction and development. FMD vaccine manufacturing follows a simple multi-step process. This white paper illustrates our collaboration with MEVAC to optimize the filtration strategies used during both upstream and downstream processing of foot and mouth disease (FMD) virus vaccine to ensure scalable, cost effective and robust GMP compliant manufacturing