Article | August 5, 2025

The Enrollment Abyss: Why Patients Drop Out Before They Even Join, And How Patient Experience Optimization Closes The Gap

Source: Jumo Health
GettyImages-2183708450-doctor-with-patient-tablet-doctors-office

Traditional clinical trial recruitment strategies focus on awareness, assuming that if patients know about a study, they will enroll. However, this thought process fails to account for the complex emotional, cognitive, and logistical barriers patients face, leading to the “Enrollment Abyss”—a critical gap where most patients drop out before reaching consent. High click-through rates and eligibility screens mean little if patients feel overwhelmed, unsupported, or unclear about next steps. Jumo Health’s Patient Experience Optimization (PXO) model transforms enrollment from a passive funnel into an active, designed experience. PXO integrates behavioral science, health literacy, and human-centered design to guide patients through the decision journey with clarity and confidence. In real-world trials, PXO has driven up to a 31% increase in consent rates and significantly reduced early-stage withdrawals.

Enrollment is not a marketing challenge; it’s an operational imperative. PXO equips clinical operations with predictable conversion metrics, better data quality, and a patient-centered system designed to close the Enrollment Abyss and sustain long-term engagement.

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