FEATURED ARTICLES

• What Is Pre-Use, Post-Sterilization Integrity Testing (PUPSIT)?

  Sterile filter integrity testing helps confirm performance, reduce risk, and support stronger processing controls as global regulatory guidance increasingly emphasizes PUPSIT where feasible.

• Filtration: The Overlooked Enabler Of Process Intensification

  Process intensification depends on more than facility changes. Smarter choices can help improve yield, throughput, and sustainability, turning an often-overlooked step into a meaningful contributor.

• Process Intensification And Other Ways To Adapt To Changing Needs

  As biologics manufacturing evolves, gain insight into why productivity depends on smarter investments, flexible production strategies, and supplier support that can address shifting modalities.

• Collaborative Supply Chain Management In A Fragmented World

  Biopharma supply chains are under pressure. As regionalization accelerates, success depends on agility, trust, and new approaches to collaboration that can withstand ongoing global uncertainty.

• Unlocking The Full Potential Of Antibody-Drug Conjugates (ADCs)

  ADCs are evolving rapidly. Gain insight into how success now hinges on managing complexity, delivery, and scalability to turn promising designs into viable therapeutic products.

• ADC Manufacturing: Practices, Challenges, And The Road Ahead

  ADCs are advancing quickly, but manufacturing complexity is rising just as fast. Key challenges in scale-up, regulation, and costs are reshaping how the next generation of therapies will be delivered.

• Keeping mAb Aggregation Low During The Final UF/DF Step

  mAb aggregation can arise from molecular properties, process conditions, and equipment‑driven stress. Learn where aggregation risk increases across downstream processing and formulation.

• Simulating PUPSIT Or Gas Purges In Bacterial Challenge Tests

  Managing PUPSIT‑related risks is a critical part of contamination control. Learn how bacterial retention studies, wetting fluids, and downstream practices influence sterility assurance.

• Product-Wet Integrity Testing: Risk-Based Strategies

  When standard water‑based integrity testing falls short, product‑wet approaches can offer a more representative alternative. Learn how risk‑based strategies are used to establish reliable test limits.

• In Vivo Manufacturing: When The Body Becomes The Bioreactor

  Breakthrough therapies are reshaping medicine, but manufacturing complexity is holding them back. Discover how rethinking production and delivery could expand reach and improve patient experience.