2nd LNP Immunogenicity and Toxicity Summit

December 11 - 13, 2023 - MA US

Hanson Wade


The 2nd LNP Immunogenicity and Toxicity Summit is set to unite 100+ PKPD, Immunology, Safety, Toxicology experts from biopharma and academia. This is your opportunity to join key opinion leaders within the industry to explore the steep progress being made in the space and actively address the field's most pressing challenges through multiple deep-dive discussions. In collaboration with Pfizer, BioNTech, Sanofi and Eli Lilly, this 3-day summit will bring together senior leaders dedicated to understanding and predicting the next wave of LNP's immunogenicity and toxicity challenges, to support drug developers to ensure smooth filing with long-term patient safety in mind. This year we are moving alongside the pharmaceutical industry and bringing the focus to accurately measuring immuno-tox of their LNP for regulatory IND filing, using different payloads in LNPs beyond mRNA and understanding the importance of accurate immunogenicity and toxicity studies for approval and patient safety. Do not miss out on the only industry forum dedicated to uncovering immunogenicity and toxicity challenges within the LNP space and takeaway: - Robust analysis of LNPs to unpick driving factors behind immune response and immune cell engagement - Preclinical models from in vitro, animal models and 3D tissue models to optimize translatability into the clinic - Understanding of LNP immunogenicity and toxicity read-outs in relation to application of vaccine, gene therapy and chronic disease - Advanced immunogenicity models to minimize anti-PEG response, and PEG alternatives to minimize adverse effects - Widened therapeutic windows and well understood dose limiting toxicities for maximal efficacious benefit - Evaluation of the LNP-payload complex beyond mRNA for next-generation development Group discounts and early bird rates are available - please visit the website for more info. Time: 9:00 AM - 5:00 PM

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