Cytiva Cell datasheets catalogs app notes

1. A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation 1/15/2025

   Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.

2. How To Successfully Isolate Your T Cells 10/7/2024

   Explore the results of a study focusing on the early stages of the CAR T cell workflow, specifically the initial washing of leukapheresis followed by the isolation of T cells.

3. Review Of Applications And Processes In Fixed-Bed Bioreactors 5/6/2024

   Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.

4. Lentiviral Vector Production Using Single-Use Bioreactors 5/6/2024

   Here, we outline a scalable and robust upstream process developed for LVV production of HEK293T cells and demonstrate how to expand HEK293T suspension cells.

5. Get Full Control Of Your T Cell Isolation 3/25/2024

   This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.

6. Using Automated Spinoculation For CAR T Cell Lentiviral Transduction 2/26/2024

   There is a growing demand for closed and automated lentiviral transduction steps in CAR T cell therapy workflows. Learn about a potential solution to address this unmet need.

7. Standardize Scale-Up And Reduce Time To Market With Mixing Cartridges 7/21/2023

   Despite the momentum of the RNA-LNP therapeutic market, significant manufacturing challenges remain. However, the right mixing could solve three of these key challenges regarding instrumentation.

8. Understanding The Microfluidic Platforms For Scaling Nanoparticle Production 10/13/2022

   Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.

9. Biacore™ SPR Systems For Titer Analysis Of Adeno-Associated Virus 10/13/2022

   We describe the performance of two assays for titer analysis of adeno-associated virus (AAV), serotype 2 and serotype 5, based on surface plasmon resonance (SPR).

10. AAV Production In Suspension HEK293 Cells With Single-Use Bioreactors 10/13/2022

    Explore how we expanded HEK293/HEK293T suspension cells from small cell culture (20 mL) in shake flasks up to a 10 L culture in a benchtop Xcellerex™ XDR-10 single-use bioreactor system.