By Wayne Koberstein, Executive Editor, Life Science Leader magazine
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Addressing vertigo and hearing loss inside the inner ear.
Sensorion is a public company in France developing new medicines for diseases of the inner ear, with two compounds in the pipeline: SENS- 111 for treating acute unilateral vestibulopathy (intense vertigo), and SENS-401 for treating hearing disorders such as sudden sensorineural hearing loss (SSNHL) and preventing others such as cisplatin-induced ototoxicity. Now in a Phase 2 trial, SENS-111 is a first-in-class, histamine H4 receptor antagonist. Entering Phase 2 development for SSNHL, SENS-401 is a 5-HT3 receptor antagonist with calcineurin inhibition mode of action.