06.21.26 -- Why Do So Many New Drug Launches Fail To Meet Expectations?

Entrenchment can be the enemy of innovation, making it hard for companies to do things differently, even when change is imperative. This week’s selections from Life Science Leader offer tips for overcoming ingrained operational behaviors, and how to spot them in real time. On supply chain, a seven-figure investment in tech upgrades for better visibility won’t move the needle if it doesn’t influence decision-making.

Shifting from an exclusive R&D focus to drug commercialization is essentially a “company maturity test,” writes Richard Lowenthal, cofounder and CEO at ARS Pharmaceuticals, in an article that shares his experiences and learnings during the process.

On the Business of Biotech, William Soliman explains why so many drug launches fail, and lays out three common launch mistakes and how to avoid them. Soliman also discusses key changes in the commercial landscape, from media channels and AI to misinformation and professional marketing.

Check out a curated selection from our partners, below, and thanks as always for reading.

Ben Comer                
Chief Editor, Life Science Leader

Mural Health clarifies participant payment complexities that can stall commercialization if operational decisions don’t align with recruitment realities.

ISPOR highlights whole-health models that connect real-world outcomes to smarter commercialization strategies beyond traditional clinical success metrics.

20/20 Onsite demonstrates how closing logistics gaps protects endpoint integrity, ensuring operational discipline translates into trustworthy, launch-ready data.

Ergomed Clinical Research shows how integrated oversight prevents costly disruptions, reinforcing agile decision-making critical for commercial readiness.

Flourish Research reveals how proactive risk management in immuno-oncology enables scalable trial models that support confident transition into market delivery.

EmVenio Clinical Research emphasizes decentralized execution that expands access while demanding operational rigor essential for sustainable commercialization success.

Siemens connects R&D, manufacturing, and supply chains with unified data strategies that transform investment into actionable, commercialization-driving decisions.