Reflecting on 20 years of experience working as a scientist in Big Pharma and biotech, Louise Modis, Ph.D., CSO at Amphista Therapeutics, shares the key elements necessary for successful drug discovery and development.
- From Bike Mechanic To Surgeon To CEO
- Mimicking The Hollywood Mindset To Develop Drugs In An Era Driven By Capital Markets
- Partnering To Advance Next Generation Treatments For Breast Cancer
- Science Does Not Sell Itself: Designing A Winning Pivotal Trial
- A Bioethicist Weighs In On Obesity Drugs
- Where Are They Now? Ironwood Pharmaceuticals
- How Cidara Got Its Molecule Back
- Now Is The Time For Philanthropic Venture Capital
COMPANIES TO WATCH
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![Dr-Stella-Sarraf_Spinogenix]( "Companies To Watch: Spinogenix")
Companies To Watch: SpinogenixSpinogenix is using small molecule drugs to regenerate synapses in patients with ALS, Alzheimer's disease, schizophrenia, glaucoma, and Fragile X syndrome.
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![Greg_Kunst]( "Companies To Watch: Aurion Biotech")
Aurion Biotech is developing what could become the first allogeneic combination cell therapy for the treatment of corneal endothelial diseases.
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![Mark Litton]( "Companies To Watch: Athira Pharma")
Athira Pharma is developing small molecule therapeutics for neurodegenerative diseases, including its lead candidate, fosgonimeton, for Alzheimer's disease.
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![Charles Hugh-Jones]( "Companies To Watch: Volastra Therapeutics")
Volastra Therapeutics is a drug discovery and development leader in the emerging field of chromosomal instability, a phenomenon that can determine how certain solid tumor cancer cells replicate and grow.
WHERE ARE THEY NOW
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![Ironwood Cover_2016]( "Where Are They Now? Ironwood Pharmaceuticals")
Where Are They Now? Ironwood PharmaceuticalsIronwood Pharmaceuticals is a smaller company than it was in 2016, when Life Science Leader wrote a feature article about its founder and mission. But Peter Hecht, Ironwood's former CEO, who now leads Tisento Therapeutics, has practiced what he preached.
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![Steven Kelly_300CMYK]( "Where Are They Now? Carisma Therapeutics")
Where Are They Now? Carisma TherapeuticsIn three years, Carisma Therapeutics has gone public, entered a broad collaboration with Moderna, and ceased development of its original CAR-Macrophage candidate, in favor of CAR-Monocyte therapies. Carisma expects to release CT-0525 Phase 1 data by the end of 2024.
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![Rachel Haurwitz]( "Where Are They Now? Caribou Biosciences")
Where Are They Now? Caribou BiosciencesCaribou Biosciences is gunning for a Phase 3 pivotal trial start in 2025 for lead candidate CB-010, after cutting its CAR-NK preclinical activities to focus exclusively on developing CB-010 and two additional allogeneic CAR-T therapies.
NEWSLETTER ARCHIVE
- 11.20.24 -- Serving The Underserved With Gates MRI's Claire Wagner, M.D.
- 11.20.24 -- Tips For Addressing Vaccine Demand – Strategies For C&G And mRNA
- 11.19.24 -- Close The TMF Compliance Gap And Future-Proof Your Operations
- 11.18.24 -- Partnering To Advance Next Generation Treatments For Breast Cancer
- 11.18.24 -- Pure In, Pure Out: Raising The Bar On Microbial Production
SPOTLIGHT
From biochemist to executive supplier to angel investor to company founder and CEO, Maria Maccecchini, Ph.D.’s independent-minded approach to neurodegenerative disease could shake up the treatment landscape.
