The Enterprisers

This column offers a deeper look into especially innovative or entrepreneurial biopharma companies, individuals, or institutions through our special lens — lessons learned, actionable info, benchmarking, best practices, etc.

  • The Enterprisers: CohBar - Producing Mitochondria Medicine
    The Enterprisers: CohBar - Producing Mitochondria Medicine

    Why shouldn’t our mitochondria want us to live long, prospering in good health? Why shouldn’t they — as symbiotic microbes turned cellular organelles with their own mini-genomes — carry genes that help ensure our healthful survival?

  • NOVAVAX: Scouting Past The Long Trail To Market
    NOVAVAX: Scouting Past The Long Trail To Market

    Clinical challenges lurk all along the pathway for any company developing new vaccine candidates and technology — and that goes at least twice for Novavax. As we go to press with this, the company is dealing with an anxious investment community about the “failed” Phase 3 trial of its RSV F vaccine in older adults, for protection against respiratory syncytial virus (RSV). (See “Press-Time Thunder.”)

  • How Rebiotix Avoids The Typical Biopharma Startup Missteps
    How Rebiotix Avoids The Typical Biopharma Startup Missteps

    A straightforward purpose and premise were the words that came to mind in my first impression of this company. Lee Jones, the CEO and cofounder of Rebiotix, describes building the company in an “of course, this is how you do it” manner. The larger issue — whether the company’s Microbiota Restoration Therapy (MRT) platform will succeed in a somewhat besieged field — can only be resolved over time. But it will most likely be biology that decides the matter, not the typical lack of clear direction or organization that plagues so many biopharma startups.

  • Life Science Leadership In Action: RespireRx
    Life Science Leadership In Action: RespireRx

    Suffocation seldom gets the credit it deserves for causing death in so many conditions — from sleep apnea to heart failure to drug overdose. But if you view the large variety of those cases at a higher resolution, you will see “respiratory failure” as the common final, fatal effect.

  • InVivo Therapeutics: Taking On Spinal-Cord Injury
    InVivo Therapeutics: Taking On Spinal-Cord Injury

    Not everyone knows someone with a spinal-cord injury. I did. We met as teenagers, shared a few years as friends but lost touch when I drifted to the opposite end of the country

  • Amarantus: Risen From The Ashes
    Amarantus: Risen From The Ashes

    One startup’s bad luck in the clinic leads to the creation of  a new company — Amarantus

  • Codagenix, A Tiny Start-Up Ready To Take On The Goliaths Of The Vaccine Industry
    Codagenix, A Tiny Start-Up Ready To Take On The Goliaths Of The Vaccine Industry

    One egg per person. That is what it takes to produce a flu vaccine. The standard, predominant method has not changed in more than 70 years.

  • The Enterprisers -- ContraVir: Mapping A Circuitous Route To Value
    The Enterprisers -- ContraVir: Mapping A Circuitous Route To Value

    If a person can be a legend, a company should be a saga. ContraVir contains both dramatic elements — a personal path through Big Pharma to small biopharma and an extended quest through a thick forest of data to find undiscovered treasure among some overlooked compounds. When I speak with CEO James Sapirstein, he takes me on a long journey full of the intertwining twists and turns of his own career and of the company he now heads. The story gives new meaning to “follow the data.”

  • The Enterprisers -- Velocity Pharmaceutical Development: A Novel Start-Up Model
    The Enterprisers -- Velocity Pharmaceutical Development: A Novel Start-Up Model

    In the typical start-up company, which parts are absolutely essential, and which parts are replaceable? The question really stems from a subaxiom of the virtual company concept, which normally places a small corporate-style management team at the center of operations and services supplied by outsourcing.

     

  • The Enterprisers -- Agile Therapeutics: Reengineering Innovation
    The Enterprisers -- Agile Therapeutics: Reengineering Innovation

    The top management team at Agile Therapeutics reflects an atypical bounty of experience and expertise for a small life sciences company. That was no accident, though it came of necessity following a near calamity. The attributes of the relatively new team proved essential in helping the company survive a key clinical trial setback that might have otherwise derailed it.

More From The Enterprisers

LIFE SCIENCE EVENTS

Alice June 26 - 28, 2017
Bangkok, CA
FDA GMP Inspections – Proven Preparation & Survival Techniques June 27, 2017
1pm-2:30pm EDT, Online Training
Price:  $299 - Includes Bonus Handouts!
Biomanufacturing Strategy Meeting USA 2017 June 27, 2017
HILTON BOSTON LOGAN AIRPORT, MA
DCAT Sharp Sourcing 2017 June 27, 2017
New Brunswick, NJ
Rational Combinations 360° June 28 - 29, 2017
New York, NY
Clinical Trial Supply Chain Strategy Meeting USA 2017 June 28, 2017
HILTON BOSTON LOGAN AIRPORT, USA, MA
Rational Combinations 360° June 28 - 29, 2017
New York, NY
How To Establish The Number of Runs Required For Process Validation June 28, 2017
1:00 - 2:00 PM EDT, Online Training
Duration:  60 Minutes
Price:  $299 - Includes Bonus Handouts!
12th Annual Conference on Nephrology & Urology 2017 July 6 - 7, 2017
Kuala Lumpur, FL
12th Annual Conference on Nephrology & Urology 2017 July 6 - 7, 2017
Kuala Lumpur, VT
Certified Copies and ALCOA-C: Essentials Post ICH GCP E6 (R2) Addendum July 10, 2017
11:00am- 12:00pm EDT, Online Training
Duration:  60 Minutes
Price:  $299 - Includes Bonus Handouts!
CRO Oversight Post ICH GCP E6 (R2) Addendum July 10, 2017
11:00am- 12:00pm EDT, Online Training
Duration:  60 Minutes
Price:  $299 - Includes Bonus Handouts!
Conducting an Effective GCP Audit of a CRO-Managed Ongoing Study: Tips and Suggestions July 11, 2017
1:00 - 2:30 PM EDT, Online Training
Duration:  90 Minutes
Price:  $299 - Includes Bonus Handouts!
Manufacturing & Laboratory Equipment Qualification – Ensuring Bullet-Proof Results July 12, 2017
1:00 - 2:00 PM EDT, Online Training
Duration:  60 Minutes
Price:  $299 - Includes Bonus Handouts!
David Richard July 17 - 18, 2017
Lisbon, AL
Daniel Smith July 20 - 22, 2017
Melbourne, ME
Clinical Study Requirements – Understanding Differences Between the US and EU July 25, 2017
1pm-2:30pm EST, Online Training
Price:  $299 - Includes Bonus Handouts!
NGS and Clinical Applications Congress: USA July 25 - 26, 2017
Philadelphia, PA